Overview
Confirm exosome isolation with confidence
When you’re ready to confirm that you’ve isolated exosomes, stick with the exosome experts at SBI. Our polyclonal rabbit anti-CD81 antibodies recognize the human and mouse forms of the protein, and are a great choice for general exosome detection, especially when used in conjunction with antibodies for other exosome markers such as the tetraspanins CD9 and CD63, as well as the heat shock protein HSP70 (if you have any questions about the best antibodies to use for your exosome project, we’re ready to help! Just email us at tech@systembio.com). And, like all of our antibodies, our anti-CD81 antibody and the included goat anti-rabbit HRP secondary antibodies are rigorously validated for exosome detection via Western blotting.
- Rigorously validated
- Hand-picked selection
- Expert exosome support
Choose the right antibody for your exosome detection needs
Cat.# | Antibody to | Notes | Link to ExoCarta entry for the human protein |
---|---|---|---|
General exosome markers | |||
EXOAB-CD9A-1 | CD9 | Tetraspanin | ExoCarta_928 |
EXOAB-CD63A-1 | CD63 | Tetraspanin | ExoCarta_967 |
EXOAB-CD81A-1 | CD81 | Tetraspanin | ExoCarta_93185 |
EXOAB-Hsp70A-1 | HSP70 | ExoCarta_3303, ExoCarta_3304, ExoCarta_3306, ExoCarta_3308, ExoCarta 3310, ExoCarta_3311 | |
EXOAB-ALIX-1 | ALIX | Programmed cell death 6 interacting protein (PDCD6IP) | ExoCarta_10015 |
EXOAB-ANXA5-1 | ANXA5-1 | Annexin A5 | ExoCarta_308 |
EXOAB-TSG101-1 | TSG101 | Tumor susceptibility gene 101 | ExoCarta_7251 |
EXOAB-FLOT1-1 | FLOT-1 | Flotillin-1 | ExoCarta_10211 |
Tissue-specific exosome markers | |||
EXOAB-CXCR4-1 | CXCR4 | Specific for B-cells, T-cells, and platelets | ExoCarta_7852 |
EXOAB-EPCAM1-1 | EpCam | Specific for cancer-derived exosomes | ExoCarta_4072 |
EXOAB-VMTN-1 | Vimentin | Specific for mesenchymal stem cells | ExoCarta_7431 |
Resources
Citations
- Perut, F, et al. (2019) Extracellular Nanovesicles Secreted by Human Osteosarcoma Cells Promote Angiogenesis. Cancers (Basel).2019 Jun 5; 11(6). PM ID:31195680
- Freitas, D, et al. (2019) Different isolation approaches lead to diverse glycosylated extracellular vesicle populations. J Extracell Vesicles.2019 Jun 3; 8(1):1621131. PM ID:31236201
- Sung, PS, Huang, TF & Hsieh, SL. (2019) Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2. Nat Commun.2019 Jun 3; 10(1):2402. PM ID:31160588
- Guo, DF, et al. (2019) The BBSome in POMC and AgRP Neurons is Necessary for Body Weight Regulation and Sorting of Metabolic Receptors. Diabetes.2019 May 24;. PM ID:31127052
- Maurel, M, et al. (2019) Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation. EMBO Mol Med.2019 Apr 30;. PM ID:31040128
- Parry, HA, et al. (2019) Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Front Physiol.2019 Apr 16; 10:436. PM ID:31040795
- Reiter, K, et al. (2019) Separation of virus-like particles and extracellular vesicles by flow-through and heparin affinity chromatography. J Chromatogr A.2019 Mar 15; 1588:77-84. PM ID:30616980
- Kim, JH, Lee, CH & Lee, SW. (2019) Exosomal Transmission of MicroRNA from HCV Replicating Cells Stimulates Transdifferentiation in Hepatic Stellate Cells. Mol Ther Nucleic Acids.2019 Mar 1; 14:483-497. PM ID:30753992
- Capello, M, et al. (2019) Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun.2019 Jan 16; 10(1):254. PM ID:30651550
- Zlotogorski-Hurvitz, A, et al. (2019) FTIR-based spectrum of salivary exosomes coupled with computational-aided discriminating analysis in the diagnosis of oral cancer. J. Cancer Res. Clin. Oncol..2019 Jan 3;. PM ID:30603907
- Loyer, X, et al. (2018) Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial Infarction. Circ. Res..2018 Mar 28;. PM ID:29592957
- Yoon, S, et al. (2017) MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity.2017 Jun 22;. PM ID:28666573
- Joy, M, et al. (2017) The Myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms. J. Biol. Chem..2017 May 25;. PM ID:28546428
- Hao, YX, et al. (2017) KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population. Oncol Lett.2017 May 1; 13(5):3608-3616. PM ID:28521461
- Hsu, YL, et al. (2017) Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1. Oncogene.2017 Apr 24;. PM ID:28436951
- LIN, F, et al. (2017) Effects of esophageal cancer cell-derived exosomes on cancer cell migration and invasion and its mechanism research. Medical Journal of Chinese People"s Liberation Army.2017 Apr 1; 42(1):307-. Link:Medical Journal of Chinese People"s Liberation Army
- Dickman, CT, et al. (2017) Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypes. Oncotarget.2017 Feb 28; 8(9):15252-15266. PM ID:28146434
- Koh, YQ, et al. (2016) Characterization of exosomal release in bovine endometrial intercaruncular stromal cells. Reprod. Biol. Endocrinol..2016 Nov 9; 14(1):78. PM ID:27829441
- Wen, S, et al. (2016) Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells. Leukemia.2016 Nov 1; 30(11):2221-2231. PM ID:27150009
- Fischer, S, et al. (2016) Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles. PLoS ONE.2016 Sep 29; 11(9):e0163665. PM ID:27684368