Overview

Supporting your studies with ready-to-go negative controls

No need to make a negative control for your miRZip™ and pGreenPuro™ shRNA studies—SBI’s already built one for you. With the miRZip & pGreenPuro shRNA Scramble Hairpin Negative Control, you get the same lentivector that expresses our miRZips and pGreenPuro shRNAs, but with a scrambled, non-targeting stem-loop sequence so you can easily control for increased miRNA effects.

The miRZip & pGreenPuro shRNA Scramble Hairpin Negative Control is available as both ready-to-transfect lentivector plasmid and ready-to-transduce pre-packaged lentivirus.

Resources

Citations

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• Wu, Q, et al. (2017) Downregulation of microRNA-448 improves isoflurane-induced learning and memory impairment in rats. MolecularMedicine Reports.2017 Jun 8;:1578-1583. Link:MolecularMedicine Reports
• Sun, J, et al. (2017) Mir-367 is downregulated in coronary artery disease and its overexpression exerts anti-inflammatory effect via inhibition of the NF-κB-activated inflammatory pathway. International Journal of Clinical and Experimental Pathology.2017 Apr 15; 10(4):4047-4057. Link:International Journal of Clinical and Experimental Pathology
• Guo, GC, et al. (2017) microRNA-761 induces aggressive phenotypes in triple-negative breast cancer cells by repressing TRIM29 expression. Cell Oncol (Dordr).2017 Apr 1; 40(2):157-166. PM ID:28054302
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• Teteloshvili, N, et al. (2017) Argonaute 2 immunoprecipitation revealed large tumor suppressor kinase 1 as a novel proapoptotic target of miR-21 in T cells. FEBS J..2017 Feb 1; 284(4):555-567. PM ID:28075055
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• Poon, VY, et al. (2016) miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1. BMC Genomics.2016 Oct 4; 17(1):777. PM ID:27716060
• Shen, X, et al. (2016) miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc. Natl. Acad. Sci. U.S.A..2016 Aug 23; 113(34):9551-6. PM ID:27512039
• Langsch, S, et al. (2016) miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.. Cancer Res..2016 Jul 15; 76(14):4160-9. PM ID:27199349
• Wang, S, et al. (2016) MicroRNA-mediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against non-small cell lung cancer. Oncotarget.2016 Jun 21; 7(25):37693-37713. PM ID:27177222
• Zheng, D, et al. (2016) Inhibition of MicroRNA 195 Prevents Apoptosis and Multiple-Organ Injury in Mouse Models of Sepsis. J. Infect. Dis..2016 May 15; 213(10):1661-70. PM ID:26704614
• Tan, Z, et al. (2016) MicroRNA-1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/β-catenin signaling in breast cancer. Oncotarget.2016 Apr 26; 7(17):24076-87. PM ID:26992223
• Lin, SC, et al. (2016) Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun.2016 Apr 25; 7:11418. PM ID:27108958
• Hong, X, et al. (2016) MiR-448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B. Oncotarget.2016 Apr 19; 7(16):22092-102. PM ID:26989077
• Liang, ML, et al. (2016) Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas. Oncotarget.2016 Apr 12; 7(15):19723-37. PM ID:26933822